{"id":5691,"date":"2024-12-18T17:46:42","date_gmt":"2024-12-18T17:46:42","guid":{"rendered":"https:\/\/new.skylarkvets.co.uk\/?p=5691"},"modified":"2025-02-08T22:12:53","modified_gmt":"2025-02-08T22:12:53","slug":"aspergillosis","status":"publish","type":"post","link":"https:\/\/www.skylarkvets.co.uk\/index.php\/2024\/12\/18\/aspergillosis\/","title":{"rendered":"Aspergillosis"},"content":{"rendered":"<p><b>About aspergillosis<\/b><\/p>\n<p><i><span style=\"font-weight: 400;\">Aspergillus fumigatus<\/span><\/i><span style=\"font-weight: 400;\"> is ubiquitous in the environment, meaning that this yeast can be found everywhere.\u00a0 However, higher density populations are commonly found in food kept in feed bins or in damp environments e.g. foods kept in a shed, and also where poor husbandry is present e.g. damp cages containing old food.\u00a0 Many (if not all) birds are exposed to <\/span><i><span style=\"font-weight: 400;\">Aspergillus<\/span><\/i><span style=\"font-weight: 400;\"> species, but most exposures do not result in clinical disease, aspergillosis.\u00a0 <\/span><i><span style=\"font-weight: 400;\">A. fumigatus<\/span><\/i><span style=\"font-weight: 400;\"> is usually an opportunistic pathogen that is <\/span><span style=\"font-weight: 400;\">NOT<\/span><span style=\"font-weight: 400;\"> contagious. However, affected birds may act as a source of fungal spores to others, and spores can be highly infectious.\u00a0\u00a0<\/span><\/p>\n<p><b>Affected species<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Any bird may be affected by <\/span><i><span style=\"font-weight: 400;\">Aspergillus <\/span><\/i><span style=\"font-weight: 400;\">species, but it is most commonly associated with birds of prey and with parrot species eating a seed-based diet.<\/span><\/p>\n<p><b>Clinical signs (symptoms)<\/b><\/p>\n<p><i>A.fumigatus<\/i> is known as a silent killer. There are no specific clinical signs that accompany this disease, but affected birds exhibit alarming weight loss for no apparent reason.\u00a0 Affected birds may have a change of pitch in, or loss of voice, which is often the first thing noticed by parrot owners.\u00a0 Birds may exhibit laboured breathing so may sit with their legs wide apart, may bob their tail to breathe, or sit with their wings held out from the body.\u00a0 This is a result of plaques of inflammatory material becoming lodged in the airways, blocking air flow. These patients are often reluctant to fly, and are often reluctant to eat, despite their weight loss.<\/p>\n<p><b>Diagnosis<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Unfortunately, the diagnosis of <\/span><i><span style=\"font-weight: 400;\">A. fumigatus<\/span><\/i><span style=\"font-weight: 400;\"> is often a diagnosis of exclusion (everything else is ruled out first). However, there may be time pressure to find and treat the cause with these birds.\u00a0 Blood tests may indicate an inflammatory process and along with the history, should form a basis of suspicion.\u00a0 X-rays should be taken and may show mottled patterns over all of the air passages. Swabs may be taken from the trachea for culture, but <\/span><i><span style=\"font-weight: 400;\">Aspergillus<\/span><\/i><span style=\"font-weight: 400;\"> species are very slow-growing organisms, so results can take weeks to months to get back.\u00a0 Ideally, the patient should undergo endoscopy, which involves the insertion of a camera into the airways.\u00a0 This enables the veterinarian to both see and sometimes to remove plaques of material present, and to directly administer treatment onto affected areas. At the same time as having endoscopy, a fluid sample can be taken for culture, directly from the airways.<\/span><\/p>\n<p><b>Aspergillosis and you<\/b><\/p>\n<p><i><span style=\"font-weight: 400;\">Aspergillus fumigatus<\/span><\/i><span style=\"font-weight: 400;\"> is zoonotic, meaning that it can be passed between species, and can be transmitted from affected birds to people.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This applies particularly to those people with chronic respiratory difficulties such as asthma, or the immunosuppressed such as the very young, the elderly, people with chronic conditions or those receiving chemotherapy.\u00a0 Fungal spores may also be readily carried as fomites on clothing. Regular contact with immunosuppressed people, who are not themselves in direct contact with the affected bird, can therefore still result in potentially very serious (if not fatal) infections.\u00a0 Strict hygiene measures must be observed if anyone in an \u2018at risk\u2019 category will be near or visited by someone near to the affected bird. Hygiene measures should include hand-washing, footwear and clothing changes as a minimum.<\/span><\/p>\n<p><b>Treatment<\/b><\/p>\n<p><span style=\"font-weight: 400;\">The first question to consider in these cases is, \u2018should we treat\u2019?\u00a0 Treatment of aspegillosis patients is anything but easy, takes a very long time and there is no guarantee that a cure can be achieved.\u00a0 The treatment is expensive, so this should also be factored in.\u00a0 In addition, <\/span><i><span style=\"font-weight: 400;\">Aspergillus<\/span><\/i><span style=\"font-weight: 400;\"> can affect those in contact with the affected bird over long periods of time, so if it is likely that the owner\u2019s health will be severely compromised, euthanasia will usually be recommended for the patient.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most effective treatment utilises endoscopy.\u00a0 The patient undergoes an anaesthetic for endoscopy every 2 weeks to 6 months to remove plaques and to apply topical treatments to the affected areas.\u00a0 Although this method is the most effective, it requires repeated general anaesthetics and repeated x-rays to monitor the regression of the plaques.\u00a0 <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another method of treatment involves nebulization with anti-fungal agents. This negates the need for anaesthesia but is not as effective as endoscopy.\u00a0 <\/span><\/p>\n<p><span style=\"font-weight: 400;\">Oral systemic anti-fungal medications may also be used, but these risk significant damage to the liver.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Any of the treatment options are a long-term commitment, with treatment lasting from a few weeks to many months.\u00a0 The response is not guaranteed, so a patient could be treated for 9-10 months but still be euthanised (put to sleep) or pass away with sudden death.\u00a0 However, treatment may be curative in some cases and these patients make good recoveries.\u00a0 In all cases, supportive treatment will be needed concurrently with the medication course, including supplementation of vitamin A and provision of nutritional support.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Any bird may be affected by Aspergillus species, but it is most commonly associated with birds of prey and with parrot species that are taking a seed-based diet.<\/p>\n","protected":false},"author":1,"featured_media":5692,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[139,190,156,171],"tags":[340,333,325,332,328,335,338,329,212,336,330,339,326,331,337,341,334,327,160],"class_list":["post-5691","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-birds","category-diseases","category-husbandry","category-poisons-and-toxins","tag-anti-fungal","tag-beathing","tag-bird-of-prey","tag-clinical-signs","tag-damp","tag-depressed","tag-endoscopy","tag-fungal","tag-hygiene","tag-immunosuppressed","tag-infectious","tag-nebulization","tag-parrot","tag-seed-based-diet","tag-treatment","tag-vitamin-a","tag-wings","tag-yeast","tag-zoonotic"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"#Any bird may be affected by Aspergillus species, but it is most commonly associated with birds of prey and with parrot species that are taking a seed-based diet. 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